Protein Details: Aquaporin-2
Protein ID
ICDB_Pro_0155
Protein Name
Aquaporin-2
Gene Name
AQP2; RO3G_15947
Organism
Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar)
Length
317 amino acids
AlphaFoldDB
AF-I1CS06-F1-model_v4.pdb
Function
Water channel required to facilitate the transport of water across membranes . Contributes to water uptake of spores during the early stages of spore germination . Aquaporins AQP1 and AQP2 act as extracellular pH sensors and enable the spores to hydrate under favorable conditions and to commence germination . Wounded vegetables and fruit present acidic pH; so the optimal pH range for germination is adapted to the relevant host pH .
Sequence
MSLRDDLTINERDPLLSSFDQRQEYNTSNNTYKVNNNSNEPSVLTLYNSDELGTSQRSSYQKFVRRSQEFKMQHREFLAEFIGTLILVLLTCGFCAEQTLNIEKSKSWLTSSLGSGLSVLIGICVAGHVSGGHLNPAITIAFWVFSGFPIRKVPMYITAQLLGAFSGAALLYSIVEPAISQFDHGKRQILGELGTAGIFGTYPPLYVGTGSAVASEVVGTAMLLLVVMVTGHPNNLPFRTAQGAMIALGVTTISLCIGYTSGFSLNPARDFGPRLFTAVAGWGIDVFTVHHYYALVPMFAPILGGLAGGFIYTVFID
PDB Structures
Ligand Binding
Binding Site
Disease
Location
DOI ID
10.1371/journal.pgen.1000549; 10.1371/journal.pone.0150543